Document Detail

Ischemic Stroke during Pregnancy and Puerperium.
MedLine Citation:
PMID:  21331336     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Ischemic stroke during pregnancy and puerperium represents a rare occurrence but it could be a serious and stressful event for mothers, infants, and also families. Whenever it does occur, many concerns arise about the safety of the mother and the fetus in relation to common diagnostic tests and therapies leading to a more conservative approach. The physiological adaptations in the cardiovascular system and in the coagulability that accompany the pregnant state, which are more significant around delivery and in the postpartum period, likely contribute to increasing the risk of an ischemic stroke. Most of the causes of an ischemic stroke in the young may also occur in pregnant patients. Despite this, there are specific conditions related to pregnancy which may be considered when assessing this particular group of patients such as pre-eclampsia-eclampsia, choriocarcinoma, peripartum cardiomiopathy, amniotic fluid embolization, and postpartum cerebral angiopathy. This article will consider several questions related to pregnancy-associated ischemic stroke, dwelling on epidemiological and specific etiological aspects, diagnostic issue concerning the use of neuroimaging, and the related potential risks to the embryo and fetus. Therapeutic issues surrounding the use of anticoagulant and antiplatelets agents will be discussed along with the few available reports regarding the use of thrombolytic therapy during pregnancy.
Elisabetta Del Zotto; Alessia Giossi; Irene Volonghi; Paolo Costa; Alessandro Padovani; Alessandro Pezzini
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Publication Detail:
Type:  Journal Article     Date:  2011-01-27
Journal Detail:
Title:  Stroke research and treatment     Volume:  2011     ISSN:  2042-0056     ISO Abbreviation:  Stroke Res Treat     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-18     Completed Date:  2011-07-14     Revised Date:  2011-07-25    
Medline Journal Info:
Nlm Unique ID:  101529024     Medline TA:  Stroke Res Treat     Country:  England    
Other Details:
Languages:  eng     Pagination:  606780     Citation Subset:  -    
Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, Italy.
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