| Ischemic Stroke during Pregnancy and Puerperium. | |
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MedLine Citation:
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PMID: 21331336 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Ischemic stroke during pregnancy and puerperium represents a rare occurrence but it could be a serious and stressful event for mothers, infants, and also families. Whenever it does occur, many concerns arise about the safety of the mother and the fetus in relation to common diagnostic tests and therapies leading to a more conservative approach. The physiological adaptations in the cardiovascular system and in the coagulability that accompany the pregnant state, which are more significant around delivery and in the postpartum period, likely contribute to increasing the risk of an ischemic stroke. Most of the causes of an ischemic stroke in the young may also occur in pregnant patients. Despite this, there are specific conditions related to pregnancy which may be considered when assessing this particular group of patients such as pre-eclampsia-eclampsia, choriocarcinoma, peripartum cardiomiopathy, amniotic fluid embolization, and postpartum cerebral angiopathy. This article will consider several questions related to pregnancy-associated ischemic stroke, dwelling on epidemiological and specific etiological aspects, diagnostic issue concerning the use of neuroimaging, and the related potential risks to the embryo and fetus. Therapeutic issues surrounding the use of anticoagulant and antiplatelets agents will be discussed along with the few available reports regarding the use of thrombolytic therapy during pregnancy. |
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Authors:
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Elisabetta Del Zotto; Alessia Giossi; Irene Volonghi; Paolo Costa; Alessandro Padovani; Alessandro Pezzini |
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Publication Detail:
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Type: Journal Article Date: 2011-01-27 |
Journal Detail:
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Title: Stroke research and treatment Volume: 2011 ISSN: 2042-0056 ISO Abbreviation: Stroke Res Treat Publication Date: 2011 |
Date Detail:
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Created Date: 2011-02-18 Completed Date: 2011-07-14 Revised Date: 2011-07-25 |
Medline Journal Info:
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Nlm Unique ID: 101529024 Medline TA: Stroke Res Treat Country: England |
Other Details:
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Languages: eng Pagination: 606780 Citation Subset: - |
Affiliation:
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Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, 25128 Brescia, Italy. |
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