| Ischemic ST-segment episodes during the initial 24 hours of ST elevation myocardial infarction predict prognosis at 1 and 5 years. | |
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MedLine Citation:
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PMID: 20106487 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The aims of the study were to assess the prognostic value of recurrent ischemic episodes during the first 24 hours in ST elevation myocardial infarction (STEMI) treated with thrombolysis and to explore those episodes as a part of a low-risk prognostic feature. DESIGN: Two hundred twenty patients with STEMI treated with thrombolysis were monitored for 24 hours with continuous online vectorcardiography assessing ST vector changes to record recurrent ischemic events. RESULTS: Ischemic events measured as an increase in ST-change vector magnitude (STC-VM) more than 50 muV for at least 2 minutes during 4- to 24-hour predicted mortality in a 5-year follow-up based on a multivariable analysis (hazard ratio, 1.18/episode; confidence interval, 1.01-1.37). The more episodes there were, the worse the prognosis. A low-risk group with a 1-year mortality of 1.9% could be identified. CONCLUSION: Continuous ST-segment monitoring during the first 24 hours of a myocardial infarction is a valuable tool for identifying high- and low-risk patients. The STC-VM events during 4 to 24 hours of the first day of a myocardial infarction predict mortality within 5 years. |
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Authors:
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Per Ottander; Johan B Nilsson; Steen M Jensen; Ulf Näslund |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-27 |
Journal Detail:
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Title: Journal of electrocardiology Volume: 43 ISSN: 1532-8430 ISO Abbreviation: J Electrocardiol Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-04-19 Completed Date: 2010-07-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0153605 Medline TA: J Electrocardiol Country: United States |
Other Details:
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Languages: eng Pagination: 224-9 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Elsevier Inc.. All rights reserved. |
Affiliation:
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Department of Cardiology, Heart Centre, Umeå University Hospital, Umeå, Sweden. per.ottander@vll.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Electrocardiography / statistics & numerical data* Female Humans Longitudinal Studies Male Middle Aged Myocardial Infarction / diagnosis*, mortality* Prevalence Prognosis Reproducibility of Results Risk Assessment Risk Factors Sensitivity and Specificity Survival Analysis Survival Rate Sweden / epidemiology |
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