| Ischaemic nature of anal fissure. | |
| | |
MedLine Citation:
|
PMID: 8653368 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Microvascular perfusion of the anoderm was assessed by laser Doppler flowmetry in 27 patients with anal fissure. Anal pressure was recorded simultaneously. Both measurements were repeated 6 weeks after lateral internal sphincterotomy and compared with those obtained from 27 controls. Means(s.d.) maximum anal resting pressure was significantly higher in those with a fissure than in controls (121.07(24.48) versus 68.78(16.97) mmHg, P < 0.001). Anodermal blood flow at the fissure site was significantly lower than at the posterior commissure of the controls (0.46(0.20) versus 0.76(0.28) V, P < 0.001). The fissure healed in 24 patients within 6 weeks of sphincterotomy. In these patients a significant pressure decrease was noted (35 per cent) which was accompanied by a consistent rise in blood flow (65 per cent) at the original fissure site. The increased internal sphincter tone in patients with a fissure reduces anodermal blood flow at the posterior midline. Reduction of anal pressure by sphincterotomy improves anodermal blood flow at the posterior midline, resulting in fissure healing. These findings provide evidence for the ischaemic nature of anal fissure. |
| | |
Authors:
|
W R Schouten; J W Briel; J J Auwerda; E J De Graaf |
Related Documents
:
|
17962078 - Technical report: effects of puva treatment on the optical properties of blood/tissue s... 8925568 - Acute reductions in blood flow and shear stress induce platelet-derived growth factor-a... 2110528 - The blood-brain barrier protects foreign antigens in the brain from immune attack. 7881368 - Input impedance of radiocephalic arteriovenous fistulae for haemodialysis access: its v... 11120368 - In vitro validation of volumetric blood flow measurement using doppler flow wire. 10374118 - Menorrhagia and uterine artery blood flow. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The British journal of surgery Volume: 83 ISSN: 0007-1323 ISO Abbreviation: Br J Surg Publication Date: 1996 Jan |
Date Detail:
|
Created Date: 1996-07-30 Completed Date: 1996-07-30 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 63-5 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, University Hospital Dijkzigt, Rotterdam, Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Anal Canal / blood supply* Female Fissure in Ano / etiology, physiopathology* Humans Ischemia / complications Laser-Doppler Flowmetry Male Manometry Microcirculation Middle Aged Pressure |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anastomotic leakage and functional outcome after anterior resection of the rectum.
Next Document: Thoracic and thoracoabdominal aortic aneurysm and dissection: an investigation based on autopsy.