Document Detail

Ischaemia following selfadministered intra-arterial injection of methylphenidate and diamorphine. A case report of treatment with intra-arterial urokinase and review.
MedLine Citation:
PMID:  3970339     Owner:  NLM     Status:  MEDLINE    
A patient presented with a painful, oedematous, cyanosed hand having injected a solution of diamorphine and methylphenidate into his radial artery. Treatment was started with heparin and vasodilators. Benefit from this was limited and a course of intra-arterial urokinase was instituted. This gave almost total resolution of the injury. The mechanisms producing ischaemia following intra-arterial injection of drugs of abuse and possible treatment are discussed.
G Corser; S Masey; G Jacob; P Kernoff; D Browne
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  40     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-03-05     Completed Date:  1985-03-05     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  AIM; IM    
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MeSH Terms
Forearm / blood supply*
Heroin / poisoning*
Injections, Intra-Arterial / adverse effects
Ischemia / chemically induced*,  drug therapy
Methylphenidate / poisoning*
Substance-Related Disorders*
Urokinase-Type Plasminogen Activator / therapeutic use
Reg. No./Substance:
113-45-1/Methylphenidate; 561-27-3/Heroin; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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