| Irritant-induced airway disorders. | |
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MedLine Citation:
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PMID: 21978855 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Thousands of persons experience accidental high-level irritant exposures each year but most recover and few die. Irritants function differently than allergens because their actions proceed nonspecifically and by nonimmunologic mechanisms. For some individuals, the consequence of a single massive exposure to an irritant, gas, vapor or fume is persistent airway hyperresponsiveness and the clinical picture of asthma, referred to as reactive airways dysfunction syndrome (RADS). Repeated irritant exposures may lead to chronic cough and continual airway hyperresponsiveness. Cases of asthma attributed to repeated irritant-exposures may be the result of genetic and/or host factors. |
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Authors:
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Stuart M Brooks; I Leonard Bernstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Immunology and allergy clinics of North America Volume: 31 ISSN: 1557-8607 ISO Abbreviation: Immunol Allergy Clin North Am Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-10-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8805635 Medline TA: Immunol Allergy Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 747-68 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Colleges of Public Health & Medicine, USF Health Science Center, University of South Florida, 13201 Bruce B. Downs Boulevard, Tampa, FL 33612, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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