| Irritant cutaneous reactions to N-methyl-2-pyrrolidone (NMP). | |
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MedLine Citation:
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PMID: 1451458 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several workers in a small electrotechnical company in Norway experienced irritant reactions of the skin after a few days of working with the solvent N-methyl-2-pyrrolidone (NMP). Due to concern about the health risk of commonly-used organic solvents, the company had chosen to use NMP when one of its products had to be treated with a solvent. After 2 days of work with NMP, 10 of the 12 involved workers displayed acute irritant contact dermatitis of the hands. According to published reports, NMP is not considered to be particularly irritant to the skin. The Safety Data Sheet of a Norwegian sales firm contained no information on cutaneous hazards, but the Safety Data Sheet of an American producer of NMP stated the risk of severe dermatitis upon prolonged contact. NMP seems to be more irritant to the human skin than reported thus far. |
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Authors:
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H L Leira; A Tiltnes; K Svendsen; L Vetlesen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Contact dermatitis Volume: 27 ISSN: 0105-1873 ISO Abbreviation: Contact Derm. Publication Date: 1992 Sep |
Date Detail:
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Created Date: 1993-01-07 Completed Date: 1993-01-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7604950 Medline TA: Contact Dermatitis Country: DENMARK |
Other Details:
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Languages: eng Pagination: 148-50 Citation Subset: IM |
Affiliation:
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Department of Occupational Medicine, University Hospital of Trondheim, Norway. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dermatitis, Irritant
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etiology* Dermatitis, Occupational / etiology* Electronics Female Hand Dermatoses / chemically induced* Humans Middle Aged Norway Pyrrolidinones / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Pyrrolidinones; 26138-58-9/N-methylpyrrolidone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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