| Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study. | |
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MedLine Citation:
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PMID: 19552631 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: No previous study has examined the comorbidity of Irritable Bowel Syndrome (IBS) and Generalized Anxiety Disorder (GAD) in a general population using standardized diagnostic methods. AIM: To examine the prevalence, comorbidity and risk correlates of IBS and GAD in a general population. METHODS: A random community-based telephone survey was conducted. The questionnaire covered symptoms of IBS, GAD, core depressive symptoms, help-seeking behaviour and functional impairment on the Sheehan Disability Scale. RESULTS: A total of 2005 participants completed the interview. The current prevalence of IBS was 5.4% and the 12-month prevalence of GAD was 4%. GAD was five times more common among IBS respondents than non-IBS respondents (OR: 5.84, P < 0.001), whereas IBS was 4.7 times more common among GAD respondents than among non-GAD respondents (OR: 6.32, P < 0.001). Core depressive symptoms (OR: 6.25, P < 0.01) and education level (OR: 5.918, P = 0.021) were risk correlates of GAD among IBS respondents. Comorbid respondents were more impaired than respondents having either disorder alone, but were not more likely to seek professional help than IBS-only respondents. CONCLUSION: Irritable Bowel Syndrome and GAD comorbidity was common and added to impairment in the community. The strong association between psychiatric morbidity and IBS observed in referral centres was not a consequence of increased help-seeking behaviour. |
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Authors:
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S Lee; J Wu; Y L Ma; A Tsang; W-J Guo; J Sung |
Publication Detail:
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Type: Journal Article Date: 2009-06-23 |
Journal Detail:
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Title: Alimentary pharmacology & therapeutics Volume: 30 ISSN: 1365-2036 ISO Abbreviation: Aliment. Pharmacol. Ther. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8707234 Medline TA: Aliment Pharmacol Ther Country: England |
Other Details:
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Languages: eng Pagination: 643-51 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong. singlee@cuhk.edu.hk |
Export Citation:
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| Comments/Corrections | |
Comment In:
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Aliment Pharmacol Ther. 2009 Nov 15;30(10):1087-8; author reply 1088-9
[PMID:
19857214
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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