Document Detail


Irrigated radiofrequency ablation catheter and electro-anatomical mapping with computerized tomography integration for renal artery sympathetic denervation.
MedLine Citation:
PMID:  23220990     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Despite over 6 decades of progress in the development of pharmacological therapy for hypertension, severe drug-resistant hypertension remains a major problem. Endovascular radiofrequency ablation of the proximal renal arteries has been reported to decrease renal artery sympathetic activity and improve long-term hypertensive control. Existing "approved" catheters for this procedure are solid tip, non-irrigated, and often difficult to steer. The existing technique uses angiography and lends itself to increased risk of renal scarring and possible stenosis. We describe a patient with multi-drug resistant hypertension who underwent catheter ablation of the bilateral renal arteries, using for the first time, an open irrigated cardiac ablation catheter with both electro-anatomical guidance and computerized tomography anatomical integration. We used "off-label" irrigated catheters, which are less prone to overheating and char formation at the catheter-surface interface, thereby decreasing the possibility of distal embolization to the renal parenchyma. The integration of electro-anatomical mapping into this procedure allowed us to avoid inadvertent circumferential ablation of the artery using electro-anatomical mapping may lower the risk of subsequent renal artery stenosis.
Authors:
Sachil Shah; Marcelo A Jimenez; Robert S Fishel
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  24     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E308-10     Citation Subset:  IM    
Affiliation:
University of Miami Miller School of Medicine Regional Campus, JFK Medical Center, Department of Internal Medicine, 5301 S. Congress Ave, Atlantis, FL 33462 USA. sshah7@med.miami.edu.
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