Document Detail

Irradiation induced kyphosis.
MedLine Citation:
PMID:  202426     Owner:  NLM     Status:  MEDLINE    
Eighty-one patients with Wilms tumor treated by irradiation and chemotherapy were studied. Despite the fact that multiple portals for irradiation were used, each crossing the midline, the amount of irradiation delivered to different parts of the vertebral body varied and it was this variation in delivered dose which produced axial skeletal deformities in 70% of the patients. Of the 57 patients with these deformities 32 had scoliosis, 22 kyphoscoliosis and 3 patients pure kyphosis; 12 patients had a kyphotic deformity of over 25 degrees, 7 patients requiring surgical correction. A high incidence of pseudarthrosis following posterior fusion has led to the preference of a 2-stage procedure, anterior interbody fusion followed by a posterior fusion with Harrington rods after 2 weeks of correction in halo femoral traction.
E J Riseborough
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  -     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  101-6     Citation Subset:  IM    
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MeSH Terms
Bacterial Infections / etiology
Child, Preschool
Kidney Neoplasms / radiotherapy
Kyphosis / etiology*,  surgery
Postoperative Complications
Prostheses and Implants / adverse effects
Radiation Injuries / complications*
Scoliosis / etiology,  surgery
Spinal Fusion / adverse effects
Surgical Wound Infection / etiology
Wilms Tumor / radiotherapy

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