| Ironing out the phosphorus problem. | |
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MedLine Citation:
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PMID: 20431575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Control of serum phosphorus remains a vexing problem in chronic kidney disease. Although novel dialysis regimens may provide excellent phosphorus control, phosphate binders remain necessary for most dialysis patients. Block et al. present a phase I clinical trial examining the safety and efficacy of SBR759, a novel non-calcium, iron-based phosphate binder. Although the risks of iron accumulation and hypocalcemia must be addressed, this phosphate binder appears to be well tolerated and effective and offers a powder-based formulation. |
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Authors:
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Joshua J Zaritsky; Isidro B Salusky |
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Publication Detail:
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Type: Comment; Journal Article; Review |
Journal Detail:
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Title: Kidney international Volume: 77 ISSN: 1523-1755 ISO Abbreviation: Kidney Int. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-30 Completed Date: 2010-08-23 Revised Date: 2013-04-05 |
Medline Journal Info:
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Nlm Unique ID: 0323470 Medline TA: Kidney Int Country: United States |
Other Details:
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Languages: eng Pagination: 845-7 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA. jzaritsky@mednet.ucla.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium
/
blood,
metabolism,
therapeutic use Calcium Phosphates / therapeutic use Calcium, Dietary / therapeutic use Humans Hypocalcemia / chemically induced, drug therapy Kidney Failure, Chronic* / blood, chemically induced, drug therapy Phosphates / blood, therapeutic use Phosphorus / blood*, therapeutic use Phosphorus, Dietary / therapeutic use Renal Dialysis Renal Insufficiency, Chronic / chemically induced, drug therapy Safety |
| Chemical | |
Reg. No./Substance:
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0/Calcium Phosphates; 0/Calcium, Dietary; 0/Phosphates; 0/Phosphorus, Dietary; 7440-70-2/Calcium; 7723-14-0/Phosphorus; 97Z1WI3NDX/calcium phosphate |
| Comments/Corrections | |
Comment On:
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Kidney Int. 2010 May;77(10):897-903
[PMID:
20375984
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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