| Iron status at 9 months of infants with low iron stores at birth. | |
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MedLine Citation:
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PMID: 12219063 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the 9-month follow-up iron status of infants born with abnormally low serum ferritin concentrations. Study design: Ten infants of >34 weeks' gestation with cord serum ferritin concentrations <5th percentile at birth (<70 microg/L) and 12 control infants with cord serum ferritin concentrations >80 microg/L had follow-up serum ferritin concentrations measured at 9 +/- 1 month of age. The mean follow-up ferritins, incidences of iron deficiency and iron-deficiency anemia, and growth rates from 0 to 12 months were compared between the two groups. RESULTS: At follow-up, the low birth ferritin group had a lower mean ferritin than the control group (30 +/- 17 vs 57 +/- 33 microg/L; P =.03), but no infant in either group had iron deficiency (serum ferritin <10 microg/L) or iron-deficiency anemia. Both groups grew equally well, but more rapid growth rates were associated with lower follow-up ferritin concentrations only in the low birth ferritin group (r = -0.52; P =.05). Both groups were predominantly breast-fed without iron supplementation before 6 months. CONCLUSIONS: Infants born with serum ferritin concentrations <5th percentile continue to have significantly lower ferritin concentrations at 9 months of age compared with infants born with normal iron status, potentially conferring a greater risk of later onset iron deficiency in the second postnatal year. |
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Authors:
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Michael K Georgieff; Sandi W Wewerka; Charles A Nelson; Raye-Ann Deregnier |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of pediatrics Volume: 141 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-09-09 Completed Date: 2002-10-09 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: AIM; IM |
Affiliation:
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Departments of Pediatrics, the Institute for Child Development, and the Center for Neurobehavioral Development, University of Minnesota, Minneapolis, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Iron-Deficiency
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epidemiology* Case-Control Studies Deficiency Diseases / epidemiology Female Fetal Growth Retardation / complications* Follow-Up Studies Growth Humans Infant Infant Nutritional Physiological Phenomena Infant, Newborn Iron / deficiency* Linear Models Male Pregnancy Pregnancy in Diabetics* United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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HD-29421/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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