Document Detail


Iron nutritional status in preterm infants fed formulas fortified with iron.
MedLine Citation:
PMID:  10375362     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To prospectively evaluate the iron nutritional status of preterm infants fed either a term (0.5 mg/dl iron) or preterm (0.9 mg/dl) formulas fortified with iron after hospital discharge. METHODS: Healthy low birthweight preterm infants were randomly assigned into three groups at the time of hospital discharge. Group A were fed an iron fortified preterm formula (0.9 mg/dl iron) until 6 months corrected age; group B, a fortified term formula (0.5 mg/l iron) until 6 months corrected age group C, the preterm formula between hospital discharge and term, then the term formula until 6 months corrected age. RESULTS: Seventy eight infants were followed up to 6 months corrected age. Iron intake from formula differed significantly between the groups (A, 1.17 mg/kg/day (SD 0.32) > C, 0. 86 mg/kg/day (SD 0.40) = B, 0.81 mg/kg/day (SD 0.23); p < 0.0001). Haemoglobin concentrations were similar to those of iron sufficient preterm infants of the same postnatal age, and term infants of the same postmenstrual age (after 3 months of age). There were no significant differences in haemoglobin concentration (p = 0.391), plasma ferritin (A vs B, p = 0.322), or in the incidence of iron deficiency (A vs B, p = 0.534). CONCLUSIONS: Iron fortified formulas containing between 0.5 and 0.9 mg/dl iron seem to meet the iron nutritional needs of preterm infants after hospital discharge.
Authors:
I J Griffin; R J Cooke; M M Reid; K P McCormick; J S Smith
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  81     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  2000-03-30     Completed Date:  2000-03-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  F45-9     Citation Subset:  AIM; IM    
Affiliation:
Neonatal Nutrition Research Group Royal Victoria Infirmary University of Newcastle-upon-Tyne, UK. igriffin@neo.bcm.tmc.edu
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Anemia, Iron-Deficiency / blood,  diet therapy
Ferritins / blood
Food, Formulated*
Hemoglobin A / analysis
Humans
Infant
Infant Food*
Infant, Newborn
Infant, Premature
Iron / administration & dosage*
Nutritional Status
Prospective Studies
Chemical
Reg. No./Substance:
7439-89-6/Iron; 9007-73-2/Ferritins; 9034-51-9/Hemoglobin A
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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