| Iron nutritional status in preterm infants fed formulas fortified with iron. | |
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MedLine Citation:
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PMID: 10375362 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To prospectively evaluate the iron nutritional status of preterm infants fed either a term (0.5 mg/dl iron) or preterm (0.9 mg/dl) formulas fortified with iron after hospital discharge. METHODS: Healthy low birthweight preterm infants were randomly assigned into three groups at the time of hospital discharge. Group A were fed an iron fortified preterm formula (0.9 mg/dl iron) until 6 months corrected age; group B, a fortified term formula (0.5 mg/l iron) until 6 months corrected age group C, the preterm formula between hospital discharge and term, then the term formula until 6 months corrected age. RESULTS: Seventy eight infants were followed up to 6 months corrected age. Iron intake from formula differed significantly between the groups (A, 1.17 mg/kg/day (SD 0.32) > C, 0. 86 mg/kg/day (SD 0.40) = B, 0.81 mg/kg/day (SD 0.23); p < 0.0001). Haemoglobin concentrations were similar to those of iron sufficient preterm infants of the same postnatal age, and term infants of the same postmenstrual age (after 3 months of age). There were no significant differences in haemoglobin concentration (p = 0.391), plasma ferritin (A vs B, p = 0.322), or in the incidence of iron deficiency (A vs B, p = 0.534). CONCLUSIONS: Iron fortified formulas containing between 0.5 and 0.9 mg/dl iron seem to meet the iron nutritional needs of preterm infants after hospital discharge. |
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Authors:
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I J Griffin; R J Cooke; M M Reid; K P McCormick; J S Smith |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Archives of disease in childhood. Fetal and neonatal edition Volume: 81 ISSN: 1359-2998 ISO Abbreviation: Arch. Dis. Child. Fetal Neonatal Ed. Publication Date: 1999 Jul |
Date Detail:
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Created Date: 2000-03-30 Completed Date: 2000-03-30 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 9501297 Medline TA: Arch Dis Child Fetal Neonatal Ed Country: ENGLAND |
Other Details:
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Languages: eng Pagination: F45-9 Citation Subset: AIM; IM |
Affiliation:
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Neonatal Nutrition Research Group Royal Victoria Infirmary University of Newcastle-upon-Tyne, UK. igriffin@neo.bcm.tmc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Anemia, Iron-Deficiency / blood, diet therapy Ferritins / blood Food, Formulated* Hemoglobin A / analysis Humans Infant Infant Food* Infant, Newborn Infant, Premature Iron / administration & dosage* Nutritional Status Prospective Studies |
| Chemical | |
Reg. No./Substance:
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7439-89-6/Iron; 9007-73-2/Ferritins; 9034-51-9/Hemoglobin A |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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