Document Detail


Iron-mediated one-pot formal nitrocyclization onto unactivated alkenes.
MedLine Citation:
PMID:  21088775     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
One-pot synthesis of heterocycles having a nitromethyl group was achieved by sequential steps that involved chloronitration of alkenes using iron(iii) nitrate nonahydrate followed by elimination and intramolecular Michael addition. This reaction provides an efficient method for the synthesis of heterocycles due to the simple experimental procedure and the use of inexpensive reagents of low toxicity.
Authors:
Tsuyoshi Taniguchi; Tatsuya Fujii; Hiroyuki Ishibashi
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Publication Detail:
Type:  Journal Article     Date:  2010-11-18
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  9     ISSN:  1477-0539     ISO Abbreviation:  Org. Biomol. Chem.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  England    
Other Details:
Languages:  eng     Pagination:  653-5     Citation Subset:  IM    
Affiliation:
School of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. tsuyoshi@p.kanazawa-u.ac.jp.
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