| Iron deposits and dietary patterns in familial combined hyperlipidemia and familial hypertriglyceridemia. | |
| | |
MedLine Citation:
|
PMID: 20645139 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Iron deposits are associated with lipid phenotype in familial hypertriglyceridemias, mainly familial combined hyperlipidemia (FCH) and familial hypertriglyceridemia (FHTG). In turn, diet plays an important role in hypertriglyceridemias although it is not known if dietary patterns are associated with iron concentration in these disorders. The objective was to determine the relationship between diet and iron deposits, measured through serum ferritin concentration, in patients with FCH and FHTG. The study was composed of 140 patients, 107 with FCH and 33 with FHTG. Subjects completed a validated 137-item food frequency questionnaire. Dividing subjects by ferritin tertiles adjusted by sex, there were no significant differences in dietary patterns except in dairy products consumption which was lower in the highest ferritin tertile. Subjects were also divided by triglycerides tertiles adjusted by sex. Those subjects in the highest tertile had lower HDL cholesterol and higher ferritin concentrations. Regarding to dietary parameters, there were significant differences in marine omega three fatty acids and vegetables presenting higher and lower consumption, respectively, those patients in the highest tertile of triglycerides. Moreover, there was not a significant correlation between dietary iron intake and any parameter, both biochemical and dietary, including ferritin concentrations. In conclusion, in patients with primary hypertriglyceridemia, triglycerides are associated with ferritin concentrations but dietary patterns are not related to iron deposits. Our results highly support the concept that the genetic mechanisms driven to hypertriglyceridemia also favor iron overload. |
| | |
Authors:
|
Rocio Mateo-Gallego; Maria Solanas-Barca; Elena Burillo; Ana Cenarro; Iva Marques-Lopes; Fernando Civeira |
Related Documents
:
|
3487999 - Evaluation of a fluorometric method for the quantitative assay of fecal hemoglobin in t... 1957929 - Reliability of the part ii board certification examination in psychiatry: interexaminer... 8568119 - Dietary ferric vs. ferrous iron in copper-deficient rats fed fructose-based diets. 3543939 - Desferrioxamine suppresses plasmodium falciparum in aotus monkeys. 15735079 - The addition of milk or yogurt to a plant-based diet increases zinc bioavailability but... 10641719 - Comparison of the bioavailability of quercetin and catechin in rats. 7783659 - Changes in plasma lipoprotein concentrations and composition in response to a low-fat, ... 2240309 - Use of fat-modified food products to change dietary fat intake of young people. 21240829 - Dietary risk assessment of organophosphorus and dithiocarbamate pesticides in a total d... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-20 |
Journal Detail:
|
Title: Journal of physiology and biochemistry Volume: 66 ISSN: 1138-7548 ISO Abbreviation: J. Physiol. Biochem. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9812509 Medline TA: J Physiol Biochem Country: Spain |
Other Details:
|
Languages: eng Pagination: 229-36 Citation Subset: IM |
Affiliation:
|
Instituto Aragonés de Ciencias de la Salud (I+CS), Unidad de Lípidos and Laboratorio de Investigación Molecular, Hospital Universitario Miguel Servet, Avda. Isabel La Católica, Zaragoza, Spain. rmateo.iacs@aragon.es |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Contribution of electron microscopy to the final diagnosis of renal biopsies in egyptian patients.
Next Document: Introduction.