Document Detail


Iron deficiency in infants: the influence of mild antecedent infection.
MedLine Citation:
PMID:  6502335     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study of 467 healthy term infants seen for routine 1-year health maintenance examination, we determined the influence of mild prior infection on the concentration of hemoglobin and other laboratory evidence of iron deficiency. In addition we studied the Hgb response in 261 infants randomized to receive a 3-month course of treatment with either iron or placebo. Infants who had had one or more clinic visits because of infection during the previous 3 months or who were reported as not being entirely well during the past month or who had an elevated sedimentation rate were more likely to have anemia or "low normal" Hgb, higher erythrocyte protoporphyrin and serum ferritin values, and lower serum iron concentration than infants who had been well. Hgb response greater than or equal to 1 gm/dl after iron treatment occurred more commonly in infants who had had prior visits because of infection. The results indicate that upper respiratory and other mild antecedent infections commonly predispose to iron deficiency (probably because of a decrease in iron absorption).
Authors:
J D Reeves; R Yip; V A Kiley; P R Dallman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  105     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-14     Completed Date:  1985-01-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  874-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Anemia, Hypochromic / blood*,  drug therapy
Blood Sedimentation
Erythrocyte Indices
Ferritins / analysis
Hemoglobins / analysis
Humans
Infant
Infection / blood*
Iron / therapeutic use
Time Factors
Transferrin / analysis
Grant Support
ID/Acronym/Agency:
200-70-09100//PHS HHS; AM 13897/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
0/Hemoglobins; 11096-37-0/Transferrin; 7439-89-6/Iron; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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