Document Detail

Iron deficiency anemia in infancy and reach and grasp development.
MedLine Citation:
PMID:  19592115     Owner:  NLM     Status:  MEDLINE    
This study assessed 9 kinematic characteristics of infants' reach and grasp to test the hypothesis that iron deficiency anemia (IDA) delays upper extremity motor development. Reach and grasp movements, recorded with a 3D-motion capture system, were compared in 9- to 10-month-old infants (4 IDA vs. 5 iron-sufficient [IS]). Based on normative motor development data available for 6 characteristics, the results indicated poorer upper extremity control in IDA infants: 2 characteristics showed statistically significant group differences despite small n, and the other 4 had strong indications for such results (effect sizes [Cohen's d]>1.2). The remaining 3 measures, for which normative studies do not show developmental changes in this age period, showed significant or moderate-to-large effect differences. Poorer upper-extremity control in IDA infants in the short-term in this study and in the long-term despite iron therapy in other studies suggests that a motor intervention may be warranted when IDA is detected in infancy.
Tal Shafir; Rosa Angulo-Barroso; Jing Su; Sandra W Jacobson; Betsy Lozoff
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2009-07-09
Journal Detail:
Title:  Infant behavior & development     Volume:  32     ISSN:  1934-8800     ISO Abbreviation:  Infant Behav Dev     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-05     Completed Date:  2010-01-12     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  7806016     Medline TA:  Infant Behav Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  366-75     Citation Subset:  IM    
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MeSH Terms
African Americans
Aging / psychology
Anemia, Iron-Deficiency / drug therapy,  psychology*
Biomechanical Phenomena
Child Development / physiology*
Data Interpretation, Statistical
Hand Strength / physiology*
Iron Compounds / therapeutic use
Iron, Dietary
Nutritional Status
Psychomotor Performance / physiology*
Upper Extremity / physiology
Videotape Recording
Grant Support
P01 HD039386/HD/NICHD NIH HHS; P01 HD039386/HD/NICHD NIH HHS; P01 HD039386-01A1/HD/NICHD NIH HHS; P01 HD039386-02/HD/NICHD NIH HHS; P01 HD039386-03/HD/NICHD NIH HHS; P01 HD039386-04/HD/NICHD NIH HHS; P01 HD039386-05/HD/NICHD NIH HHS; P01 HD039386-06A1/HD/NICHD NIH HHS; P01 HD039386-06A19004/HD/NICHD NIH HHS; P01 HD039386-06A19005/HD/NICHD NIH HHS; P01 HD039386-07/HD/NICHD NIH HHS; P01 HD039386-079004/HD/NICHD NIH HHS; P01 HD039386-079006/HD/NICHD NIH HHS
Reg. No./Substance:
0/Iron Compounds; 0/Iron, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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