| Iron deficiency and anaemia in heart failure: understanding the FAIR-HF trial. | |
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MedLine Citation:
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PMID: 20855375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Treatment of anaemia in patients with chronic heart failure (CHF) and reduced left ventricular ejection fraction has traditionally focused on erythropoietin-stimulating agents. However, recent studies have shown that treatment with intravenous (IV) iron can improve the symptoms and quality of life in patients with CHF and iron deficiency (ID), with or without anaemia. The management of ID is becoming an important therapeutic target in patients with CHF, and in this article, we will review iron metabolism in the context of anaemia and heart failure. We will also focus on the importance of diagnosing and treating ID, preferably with IV iron preparations, in patients with CHF. |
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Authors:
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José González-Costello; Josep Comín-Colet |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-09-20 |
Journal Detail:
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Title: European journal of heart failure Volume: 12 ISSN: 1879-0844 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-22 Completed Date: 2011-03-14 Revised Date: 2011-06-08 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1159-62 Citation Subset: IM |
Affiliation:
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Heart Failure and Cardiac Transplant Unit, Department of Cardiology, Hospital Universitari de Bellvitge, Institut d'Investigació Biomédica de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain. jgcostello@hotmail.com |
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Iron-Deficiency
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epidemiology*,
physiopathology,
therapy Animals Ferritins / blood Heart Failure / epidemiology*, metabolism Humans Intestinal Absorption / physiology Iron / administration & dosage, deficiency*, metabolism Stroke Volume Transferrin / analysis |
| Chemical | |
Reg. No./Substance:
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11096-37-0/Transferrin; 7439-89-6/Iron; 9007-73-2/Ferritins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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