Document Detail

Iron deficiency and anaemia in heart failure: understanding the FAIR-HF trial.
MedLine Citation:
PMID:  20855375     Owner:  NLM     Status:  MEDLINE    
Treatment of anaemia in patients with chronic heart failure (CHF) and reduced left ventricular ejection fraction has traditionally focused on erythropoietin-stimulating agents. However, recent studies have shown that treatment with intravenous (IV) iron can improve the symptoms and quality of life in patients with CHF and iron deficiency (ID), with or without anaemia. The management of ID is becoming an important therapeutic target in patients with CHF, and in this article, we will review iron metabolism in the context of anaemia and heart failure. We will also focus on the importance of diagnosing and treating ID, preferably with IV iron preparations, in patients with CHF.
José González-Costello; Josep Comín-Colet
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-09-20
Journal Detail:
Title:  European journal of heart failure     Volume:  12     ISSN:  1879-0844     ISO Abbreviation:  Eur. J. Heart Fail.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-22     Completed Date:  2011-03-14     Revised Date:  2011-06-08    
Medline Journal Info:
Nlm Unique ID:  100887595     Medline TA:  Eur J Heart Fail     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1159-62     Citation Subset:  IM    
Heart Failure and Cardiac Transplant Unit, Department of Cardiology, Hospital Universitari de Bellvitge, Institut d'Investigació Biomédica de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
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MeSH Terms
Anemia, Iron-Deficiency / epidemiology*,  physiopathology,  therapy
Ferritins / blood
Heart Failure / epidemiology*,  metabolism
Intestinal Absorption / physiology
Iron / administration & dosage,  deficiency*,  metabolism
Stroke Volume
Transferrin / analysis
Reg. No./Substance:
11096-37-0/Transferrin; 7439-89-6/Iron; 9007-73-2/Ferritins

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