Document Detail


Iron and Parkinson's disease: chelators to the rescue?
MedLine Citation:
PMID:  14552066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The essential metal iron has long been implicated in the neuronal damage associated with Parkinson's disease. Recent findings show that iron chelation may prevent the reductions in dopamine and motor disturbances associated with this disease, and suggest the need to examine the role of dietary iron and the use of metal chelators in neurodegenerative disorders.
Authors:
Cathy W Levenson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition reviews     Volume:  61     ISSN:  0029-6643     ISO Abbreviation:  Nutr. Rev.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-10-13     Completed Date:  2003-11-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0376405     Medline TA:  Nutr Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-3     Citation Subset:  IM    
Affiliation:
Florida State University, Program in Neuroscience, Department of Nutrition, Food and Exercise Sciences, Tallahassee, FL 32306-4340, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Iron / metabolism*
Iron Chelating Agents / metabolism*,  therapeutic use
Nerve Degeneration
Neuroprotective Agents / therapeutic use
Parkinson Disease / drug therapy,  etiology,  metabolism*
Chemical
Reg. No./Substance:
0/Iron Chelating Agents; 0/Neuroprotective Agents; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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