Document Detail


Iron Balance in Regular Blood Donors.
MedLine Citation:
PMID:  21760763     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
SUMMARY: BACKGROUND: Numerous reports have shown that iron stores decrease in blood donors after donation. As we need healthy donors, it is essential to test hemoglobin and ferritin levels for preventing reduced of iron stores in donors. METHODS: This study was conducted on 235 healthy men. The donors were divided into three groups: group I) control group with no donation; group II)  case group 1 with two donations within 1 year; group III)  case group 2 with three donations within 1 year. RESULTS: The mean level of hemoglobin was 15.9 and 14.7 g/dl in the control group and in the case group, respectively (p < 0.0000). The mean level of serum ferritin in group I, II and III, was 108, 56 and 26 μg/l, respectively (p < 0.0000). When studying various stages of iron deficiency in donors, it could be shown that 58% of group III donors but only 1% of control group donors had a negative iron balance. Moreover, iron deficiency anemia was observed in 20% of group III donors. CONCLUSION: Just measuring the hemoglobin level is not sufficient for selecting donors. In addition, testing of the ferritin level and iron supplementation are recommended in regular donors with more than one donation per year.
Authors:
Zahra Mozaheb; Mohamad Khayami; Delaram Sayadpoor
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-11
Journal Detail:
Title:  Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie     Volume:  38     ISSN:  1660-3818     ISO Abbreviation:  -     Publication Date:  2011  
Date Detail:
Created Date:  2011-7-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101176417     Medline TA:  Transfus Med Hemother     Country:  -    
Other Details:
Languages:  ENG     Pagination:  190-194     Citation Subset:  -    
Affiliation:
Department of Hematology-Oncology of Mashhad University of Medical Science, Blood Transfusion Organization of Mashhad, Iran.
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