Document Detail

Iris color: validation of a new classification and distribution in a Spanish population-based sample.
MedLine Citation:
PMID:  19551689     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To design and validate a standard, simple, and reliable iris color classification and to study its distribution in a Spanish population. Iris color has a geographic distribution and has been correlated with different ocular diseases. However, there is no standard and validated iris color classification allowing comparison among different studies. METHODS: Classification was made in three grades (blue-gray, hazel-green, brown) and was validated by 3 independent readers. Initially, a preliminary study was made in 50 iris photographs to detect technical hitches. Afterwards, based on this procedure, 221 iris photographs were graded. RESULTS: Measures of interobserver reliability were 0.786 by kappa index with an agreement of 89.6%.Iris color distribution in the Spanish cohort was blue-grey 16.29%, hazel-green 55.2%, and brown 28.5%. CONCLUSIONS: This classification is simple, reliable, and easy to use in clinical research and by ophthalmologists or generalists in practice. The Spanish cohort from this study shows a different iris color distribution from those previously published in other countries.
Yerena Muiños Díaz; Maria A Saornil; Ana Almaraz; Mari F Muñoz-Moreno; Ciro García; Ruperto Sanz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  European journal of ophthalmology     Volume:  19     ISSN:  1120-6721     ISO Abbreviation:  Eur J Ophthalmol     Publication Date:    2009 Jul-Aug
Date Detail:
Created Date:  2009-06-24     Completed Date:  2009-11-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9110772     Medline TA:  Eur J Ophthalmol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  686-9     Citation Subset:  IM    
Ophthalmology Department, Hospital Povisa, Pontevedra, Vigo, Spain.
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MeSH Terms
Classification / methods*
Eye Color*
Observer Variation
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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