Document Detail

Ipecac administration in children younger than 1 year of age.
MedLine Citation:
PMID:  2865716     Owner:  NLM     Status:  MEDLINE    
The efficacy of ipecac syrup in the induction of emesis and safety of its administration was studied in 105 poison-exposed infants 6 through 11 months of age (study subjects) and compared prospectively with 302 poison-exposed infants and children 12 through 35 months of age who served as age controls. Of the 105 study subjects 101 (96.2%) vomited. The failure of ipecac to induce emesis in six patients (four of 105 study subjects two of 302 age control subjects) is comparable with ipecac failure rates reported elsewhere. The frequency of side effects caused by ipecac syrup did not differ between study and control subjects. There were no serious medical complications resulting from the administration of ipecac syrup. When not readily available at home, ipecac administration was delayed an additional 21.8 minutes if obtained from a pharmacy and 38.4 minutes if obtained from an emergency department. Because of the time delay and the increased health care cost, home rather than emergency department administration of ipecac should be advised. These data demonstrate that ipecac syrup effectively induces emesis and is safe for home administration to poisoned infants 6 to 11 months old.
T L Litovitz; W Klein-Schwartz; G M Oderda; N J Matyunas; S Wiley; R L Gorman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  76     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1985 Nov 
Date Detail:
Created Date:  1985-11-25     Completed Date:  1985-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  761-4     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Child, Preschool
Emergency Service, Hospital
Home Nursing
Ipecac / adverse effects,  therapeutic use*
Poisoning / drug therapy*
Prospective Studies
Time Factors
Vomiting / chemically induced*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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