Document Detail


Iopamidol: new, nonionic contrast agent for excretory urography.
MedLine Citation:
PMID:  6607602     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Iopamidol, a new, nonionic contrast agent, was evaluated in 18 patients undergoing excretory urography. None of the 18 patients experienced any side effects or adverse reactions. No abnormalities were noted in serum chemistries, complete blood cell counts, urinalyses, or electrocardiograms. The half-life of iopamidol in 17 patients with normal renal function was 2.5 hr. The urograms were judged to be of good or excellent quality in 15 of 16 patients using doses of 200 and 250 mg l/kg of iopamidol. Two patients who were studied using a dose of only 120 mg l/kg had urograms rated poor. Fifteen iopamidol urograms (mean iodine dose, 17.4 g) were compared in a blind fashion with 15 meglumine diatrizoate studies (iodine dose, 29 g). No qualitative difference could be detected between the two groups of urograms. Iopamidol may provide equal-quality diagnostic studies with a lower iodine dose and perhaps greater safety than the currently used ionic agents.
Authors:
W M Thompson; W L Foster; R A Halvorsen; N R Dunnick; A J Rommel; M Bates
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  142     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-03-05     Completed Date:  1984-03-05     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  329-32     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Contrast Media* / toxicity
Diatrizoate Meglumine / diagnostic use
Half-Life
Humans
Iopamidol
Iothalamic Acid / analogs & derivatives*,  diagnostic use,  toxicity
Male
Middle Aged
Urography
Chemical
Reg. No./Substance:
0/Contrast Media; 131-49-7/Diatrizoate Meglumine; 2276-90-6/Iothalamic Acid; 62883-00-5/Iopamidol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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