Document Detail


Ionizing radiations in pregnancy and teratogenesis: a review of literature.
MedLine Citation:
PMID:  15925481     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present paper is a review of the data available in the literature concerning the prenatal exposure to radiation evaluating the reported teratogenic effect. We have particularly focused on the fetal effects of maternal ionising radiation exposure, both diagnostic and occupational, particularly in terms of congenital anomalies and birth weight. Ionising radiation represents a possible teratogen for the fetus, but this risk has been found to be dependent on the dosage and the effects correlatable to the gestational age at exposure. Recently, of particularly note is the fact that maternal thyroid exposure to diagnostic radiation has been associated with a slight reduction in the birth weight. Inadvertent exposure from diagnostic procedures in pregnancy doesn't usually increase the natural risk of congenital anomalies but creates a considerable state of maternal anxiety. Diagnostic radiological procedures should be avoided in pregnant women unless the information cannot be obtained by other techniques.
Authors:
M De Santis; E Di Gianantonio; G Straface; A F Cavaliere; A Caruso; F Schiavon; R Berletti; M Clementi
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Reproductive toxicology (Elmsford, N.Y.)     Volume:  20     ISSN:  0890-6238     ISO Abbreviation:  Reprod. Toxicol.     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-07-11     Completed Date:  2005-09-27     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8803591     Medline TA:  Reprod Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  323-9     Citation Subset:  IM    
Affiliation:
Telefono Rosso-Teratology Information Service, Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy. marcodesantis@rm.unicatt.it
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Radiation-Induced*
Adult
Animals
Birth Weight / radiation effects
Dose-Response Relationship, Radiation
Female
Humans
Maternal Exposure / adverse effects*
Occupational Exposure / adverse effects
Pregnancy
Prenatal Exposure Delayed Effects*
Radiation Dosage
Radioactive Hazard Release
Radiography / adverse effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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