Document Detail

Ionized calcium monitoring during liver transplantation.
MedLine Citation:
PMID:  3307683     Owner:  NLM     Status:  MEDLINE    
Ionized calcium concentration was measured in five patients undergoing liver transplantation. Varying degrees of decreased ionized calcium were observed in all cases and can be attributed to the chelation of calcium by the citrate added during blood transfusions, the inability of the patient to metabolize citrate by the liver during the anahepatic phase of the transplant, and hemodilution of the blood volume with the perfusion prime during venovenous bypass. Calcium chloride was administered when necessary as guided by ionized calcium measurements to restore concentrations to levels that maintain adequate cardiac output. Because of the serious hemodynamic consequences of severe hypocalcemia, regular monitoring of ionized calcium concentration is necessary during this procedure. Total calcium levels are not reliable for this because they do not reflect the extent of anion binding.
A H Wu; A Bracey; C W Bryan-Brown; J V Harper; M F Burritt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  111     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-10-21     Completed Date:  1987-10-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  935-8     Citation Subset:  AIM; IM    
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MeSH Terms
Calcium / administration & dosage,  blood*
Citrates / administration & dosage,  metabolism*
Hypocalcemia / complications,  prevention & control
Liver / metabolism
Liver Transplantation*
Reg. No./Substance:
0/Citrates; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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