Document Detail

Ion exchange method for determining mephentermine sulfate in drug formulations: collaborative study.
MedLine Citation:
PMID:  621195     Owner:  NLM     Status:  MEDLINE    
Ion exchange chromatography is used to separate mephentermine sulfate from drug formulations. The drug is subsequently measured by ultraviolet spectrophotometry. Assays on 4 commercial samples of tablets and injectables gave recoveries from 97.6 to 104% of declared. A collaborative study involving 2 tablet and 2 liquid formulations gave mean recoveries ranging from 94.7 to 99.3% and coefficients of variation from 1.39 to 2.00%.
R Chu; E J Friedman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal - Association of Official Analytical Chemists     Volume:  61     ISSN:  0004-5756     ISO Abbreviation:  J Assoc Off Anal Chem     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  7505559     Medline TA:  J Assoc Off Anal Chem     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  60-4     Citation Subset:  IM    
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MeSH Terms
Chromatography, Ion Exchange / methods
Mephentermine / analysis*
Solutions / analysis
Tablets / analysis
United States
United States Food and Drug Administration
Reg. No./Substance:
0/Solutions; 0/Tablets; 100-92-5/Mephentermine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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