Document Detail

Iodine status of pregnant women and their progeny in the Minho Region of Portugal.
MedLine Citation:
PMID:  18976166     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Iodine sufficiency is particularly necessary throughout pregnancy, given its recognized impact on psychomotor performance of the offspring. There are no recent reports about iodine status or supplementation in Portugal, a country that the International Council for Control of Iodine Deficiency Disorders considered, in 2004, to have probably reached iodine sufficiency. The objective of this study was to evaluate in the Minho region of Portugal the iodine status of women throughout pregnancy and after delivery, and of their offspring. METHODS: Urinary iodine concentration (UI) was determined in 78 nonpregnant premenopausal women, in 140 pregnant women in the three trimesters of pregnancy and after delivery, and in their 142 offspring. Milk iodine concentration was determined at day 3 and 3 months after delivery. The thyroid volume was determined in women in the third trimester of pregnancy and 3 months after delivery and in infants at 3 months of age. RESULTS: Based on the World Health Organization criteria, both nonpregnant and pregnant women had iodine deficiency (ID), as documented by median UI of <75 microg/L and milk iodine concentration of <100 microg/L. Goiter was observed in 14% of the pregnant women. Concordant with the mother's ID, median neonatal UI was low (71 and 97 microg/L at 3 days and 3 months of age). CONCLUSION: Portuguese women of the Minho region have an inadequate iodine intake, which may compromise the potential for full psychomotor development of their progeny. These observations suggest that iodine supplementation should be implemented throughout pregnancy and lactation in Portugal.
Maria J Costeira; Pedro Oliveira; Susana Ares; Gabriella Morreale de Escobar; Joana A Palha
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  19     ISSN:  1557-9077     ISO Abbreviation:  Thyroid     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  United States    
Other Details:
Languages:  eng     Pagination:  157-63     Citation Subset:  IM    
Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.
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MeSH Terms
Fish Products
Goiter / epidemiology
Infant, Newborn
Iodine / deficiency*,  urine
Maternal Nutritional Physiological Phenomena
Milk, Human / chemistry
Nutritional Status
Portugal / epidemiology
Pregnancy Complications / epidemiology,  urine*
Thyroid Gland / pathology
Thyrotropin / analysis
Reg. No./Substance:
7553-56-2/Iodine; 9002-71-5/Thyrotropin

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