Document Detail


Iodine-131-labeled Meta-Iodobenzylguanidine Therapy of Children with Neuroblastoma: Program Planning and Initial Experience.
MedLine Citation:
PMID:  21803185     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Patients with high-risk neuroblastoma have a poor prognosis, especially in cases of recurrent or relapsed disease. Iodine-131-labeled meta-iodobenzylguanidine ((131)I-MIBG) can be an effective and relatively well-tolerated agent for the treatment of refractory neuroblastoma. Establishing an MIBG therapy program requires a great deal of planning, availability of hospital resources, and the commitment of individuals with training and expertise in multiple disciplines. Providing (131)I-MIBG therapy requires physical facilities and procedures that permit patient care in compliance with the standards for occupational and community exposure to radiation. Establishment of a successful (131)I-MIBG therapy program also requires a detailed operational plan and appropriate education for caregivers, parents, and patients.
Authors:
Suzanne Shusterman; Frederick D Grant; William Lorenzen; Royal T Davis; Stephen Laffin; Laura A Drubach; Frederic H Fahey; S Ted Treves
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in nuclear medicine     Volume:  41     ISSN:  1558-4623     ISO Abbreviation:  Semin Nucl Med     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1264464     Medline TA:  Semin Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  354-63     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Pediatric Oncology, Dana-Farber Cancer Center, Boston, MA; Division of Hematology/Oncology, Department of Medicine, Children's Hospital Boston, Boston, MA.
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