Document Detail


Iodinated silicone-an antibacterial alloplastic material.
MedLine Citation:
PMID:  319467     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Iodine is readily miscible in silicones and will pass freely into and out of this material at highly predictable and constant rates. Iodinated silicone is thus an effective, controlled-rate delivery system for molecular iodine. This delivery system was shown to produce bacteriostatic and bactericidal effects in vitro, and at least bacteriostatic effects in vivo. Iodinated silicone produced a protective effect against the morbidity of infection in the mouse.
Authors:
W D Morain; L M Vistnes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Plastic and reconstructive surgery     Volume:  59     ISSN:  0032-1052     ISO Abbreviation:  Plast. Reconstr. Surg.     Publication Date:  1977 Feb 
Date Detail:
Created Date:  1977-03-15     Completed Date:  1977-03-15     Revised Date:  2011-02-16    
Medline Journal Info:
Nlm Unique ID:  1306050     Medline TA:  Plast Reconstr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-22     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Bacteria / drug effects*
Diffusion
Escherichia coli / drug effects
Iodine / pharmacology*
Kinetics
Mice
Mice, Inbred Strains
Models, Biological
Silicones / pharmacology*
Staphylococcus / drug effects
Chemical
Reg. No./Substance:
0/Silicones; 7553-56-2/Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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