Document Detail

Iodinated contrast media and contrast-induced nephropathy: is there a preferred cost-effective agent?
MedLine Citation:
PMID:  18460711     Owner:  NLM     Status:  MEDLINE    
Over 20 years have passed since the introduction of the tri-iodinated low-osmolar nonionic contrast agents such as iopamidol, iohexol, ioversol and iopromide. During this time, most cardiology practices have switched to these nonionic agents to avoid the nuisance side effects and cardiac adverse events associated with the older ionic contrast agents. Although the improved tolerability of the nonionic agents is generally attributed to their decreased osmolality (approximately half that of the older ionic contrast agents), in fact, these contrast agents also differ from the older agents in their ionicity, viscosity and direct chemotoxicity. The impact of these properties on safety, together with cost differences, should be considered when selecting a contrast agent.
Samin K Sharma
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  20     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-07     Completed Date:  2008-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  245-8     Citation Subset:  IM    
Mount Sinai Hospital, Box 1030, One Gustave Levy Place, New York, NY, 10029-6574, USA.
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MeSH Terms
Cardiovascular Diseases / diagnosis*
Contrast Media / adverse effects*,  economics*
Kidney Diseases / chemically induced*
Triiodobenzoic Acids / adverse effects*
Reg. No./Substance:
0/Contrast Media; 0/Triiodobenzoic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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