| Iodinated contrast agents. Effect on ATP: creatine N-phosphotransferase isoenzymes in arterial wall. | |
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MedLine Citation:
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PMID: 6832935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the arterial wall, ATP:creatine N-phosphotransferase (E.C.2.7.3.2) is present in the form of its three isoenzymes, MM, MB, and BB, the latter being predominant. Six iodinated contrast agents in routine angiographic use were examined from the point of view of their effects in vitro on the isoenzymes of ATP:creatine N-phosphotransferase from the arterial wall, compared with their effects on the same isoenzymes in other organs. There is a clear inhibitory effect from the contrast agents on all organs, but it is least marked for the arterial wall. Furthermore, nonionic compounds have far less enzyme-inhibitory effect than ionic compounds. |
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Authors:
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C Canillot; J Etienne; F Borson; J Guidollet; M Amiel; P Louisot |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Investigative radiology Volume: 18 ISSN: 0020-9996 ISO Abbreviation: Invest Radiol Publication Date: 1983 Jan-Feb |
Date Detail:
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Created Date: 1983-05-05 Completed Date: 1983-05-05 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0045377 Medline TA: Invest Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 81-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aorta / drug effects, enzymology Arteries / drug effects*, enzymology Brain / enzymology Contrast Media / pharmacology* Creatine Kinase / metabolism* Diatrizoate / pharmacology Dogs Iopamidol Iothalamic Acid / analogs & derivatives, pharmacology Isoenzymes Metrizamide / pharmacology Muscles / enzymology Myocardium / enzymology |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Isoenzymes; 117-96-4/Diatrizoate; 2276-90-6/Iothalamic Acid; 28179-44-4/ioxitalamic acid; 31112-62-6/Metrizamide; 62883-00-5/Iopamidol; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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