Document Detail


Involvement of trihydroxyconjugated bile salts in cholesterol assimilation by bifidobacteria.
MedLine Citation:
PMID:  9003583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the conditions of cholesterol assimilation,various strains of Bifidobacterium species were cultured in the presence of cholesterol and bile salts. During culturing, Bifidobacterium breve ATCC 15700 assimilates cholesterol in the presence of oxgall at pH values lower than 6. This strain was selected to study the influence of conjugated (taurocholic acid) and deconjugated (cholic acid) bile salts on cholesterol assimilation. B. breve ATCC 15700 assimilated cholesterol(up to 51%) when cultures were undertaken in the presence of taurocholic acid, whereas less than 13% of the initial amount ofcholesterol was measured in the cells in the presence of cholic acid. Cultured in the presence of six individual di- or trihydroxyconjugated bile salts, bifidobacteria strains assimilated cholesterol. This assimilation appeared to be more important in the presence of trihydroxyconjugated bile salts (tauro- and glycocholic acids). It is concluded thattrihydroxyconjugated bile salts are involved in the assimilation of cholesterol by bifidobacteria.
Authors:
K Tahri; J P Grill; F Schneider
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current microbiology     Volume:  34     ISSN:  0343-8651     ISO Abbreviation:  Curr. Microbiol.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-03-21     Completed Date:  1997-03-21     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  7808448     Medline TA:  Curr Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  79-84     Citation Subset:  B    
Affiliation:
Université Henri Poincaré-Nancy I, Laboratoire de Chimie Biologique I, BP 239, 54506 Vandoeuvre lès Nancy Cedex, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bifidobacterium / growth & development,  metabolism*
Bile / metabolism*
Cattle
Cholagogues and Choleretics / pharmacology
Cholesterol / analysis,  metabolism*,  pharmacology*
Cholic Acid
Cholic Acids / pharmacology
Kinetics
Taurocholic Acid / pharmacology
Chemical
Reg. No./Substance:
0/Cholagogues and Choleretics; 0/Cholic Acids; 57-88-5/Cholesterol; 81-24-3/Taurocholic Acid; 81-25-4/Cholic Acid

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