Document Detail

Involvement of right ventricle in left ventricular hypertrophic cardiomyopathy: analysis by pulsed Doppler tissue imaging.
MedLine Citation:
PMID:  11916607     Owner:  NLM     Status:  MEDLINE    
AIMS: This study uses pulsed Doppler tissue imaging to analyse right ventricular myocardial function and its interaction with left ventricle in hypertrophic cardiomyopathy involving ventricular septum. METHODS AND RESULTS: Thirty-four patients with septal hypertrophic cardiomyopathy and 30 normal subjects, comparable for sex, age, body mass index and heart rate, underwent complete standard Doppler echocardiography and pulsed Doppler tissue imaging of both posterior septum and right ventricular free wall, calculating myocardial velocities and both systolic and diastolic time intervals. Except for peak velocity A, the other Doppler tricuspid inflow measurements were significantly impaired in hypertrophic cardiomyopathy, without changes of tricuspid annular systolic excursion. Right ventricular Doppler tissue imaging showed longer right ventricular myocardial relaxation time in hypertrophic cardiomyopathy than in controls (P<0.00001), without a significant difference from other myocardial diastolic and systolic measurements. In the overall population, Doppler measurements of right and left ventricular inflow were not significantly associated, while (with the exception of myocardial deceleration time) all the other myocardial systolic and diastolic measurements derived by tissue imaging were directly related to the homologous septal myocardial indexes. In addition, a significant inverse relation was found between septal wall thickness and myocardial relaxation index (right-left myocardial relaxation time/right ventricular relaxation time x 100). CONCLUSIONS: This study shows the usefulness of pulsed Doppler tissue imaging to detect impairment of right ventricular myocardial function and to provide evidence about ventricular interaction in forms of hypertrophic cardiomyopathy which involve interventricular septum.
S Severino; P Caso; S Cicala; M Galderisi; L de Simone; A D'Andrea; A D'Errico; N Mininni
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  1     ISSN:  1525-2167     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2002-03-27     Completed Date:  2002-05-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  281-8     Citation Subset:  IM    
Divisione di Cardiologia, Azienda Ospedaliera V. Monaldi, Università Federico II di Napoli, Italy.
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MeSH Terms
Blood Flow Velocity / physiology
Body Mass Index
Cardiomyopathy, Hypertrophic / complications*,  physiopathology,  ultrasonography
Echocardiography, Doppler, Pulsed
Heart Rate / physiology
Heart Septum / pathology,  ultrasonography
Heart Ventricles / pathology*,  ultrasonography
Hypertrophy, Left Ventricular / complications*,  physiopathology,  ultrasonography
Image Enhancement
Italy / epidemiology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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