| Involvement of phospholipids in resistance and adaptation of Escherichia coli to acid conditions and to long-term survival. | |
| | |
MedLine Citation:
|
PMID: 12951243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In Escherichia coli membranes, three major phospholipids are formed: phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and cardiolipin (CL). We report here the survival of mutants lacking either PE or both PG and CL at an acid pHo and during long-term survival experiments. Stationary phase cultures of E. coli lacking PE are much more sensitive to acid shock (pHo 3) than the wild-type strain. Moreover, in the strain lacking PE, long-term survival in stationary phase is impaired and after 5 days no viable cells are recovered. The survival of an exponential phase culture to acid shock is known to be increased if the culture is exposed to moderately acid conditions (pHo 5) prior to a shift to pHo 3. If either PE or both PG and CL are missing, the exposure to pHo 5 does not increase the survival at pHo 3. |
| | |
Authors:
|
Sylvain Canet; Martine Heyde; Raymond Portalier; Patrick Laloi |
Related Documents
:
|
6980013 - Purification and characterization of an n-acylphosphatidylserine from rhodopseudomonas ... 7176823 - Effect of chlorpromazine on rat arterial lipid synthesis, in vitro. 6140003 - Adrenergic inhibition of branched-chain 2-oxo acid dehydrogenase in rat diaphragm muscl... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: FEMS microbiology letters Volume: 225 ISSN: 0378-1097 ISO Abbreviation: FEMS Microbiol. Lett. Publication Date: 2003 Aug |
Date Detail:
|
Created Date: 2003-09-02 Completed Date: 2003-12-10 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7705721 Medline TA: FEMS Microbiol Lett Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 207-11 Citation Subset: IM |
Affiliation:
|
Unité de Microbiologie et Génétique, UMR CNRS 5122, Bât A. Lwoff, Université Lyon 1, F-69622 Villeurbanne Cedex, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adaptation, Physiological* CDPdiacylglycerol-Serine O-Phosphatidyltransferase / genetics, metabolism Cardiolipins / physiology Cell Membrane / chemistry Colony Count, Microbial Escherichia coli / genetics, growth & development, metabolism, physiology* Hydrogen-Ion Concentration Mutagenesis, Insertional Phosphatidylethanolamines / physiology Phosphatidylglycerols / physiology Phospholipids / physiology* Transferases (Other Substituted Phosphate Groups) / genetics, metabolism |
| Chemical | |
Reg. No./Substance:
|
0/Cardiolipins; 0/Phosphatidylethanolamines; 0/Phosphatidylglycerols; 0/Phospholipids; EC 2.7.8.-/Transferases (Other Substituted Phosphate Groups); EC 2.7.8.5/CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; EC 2.7.8.8/CDPdiacylglycerol-Serine O-Phosphatidyltransferase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: GASP phenotype: presence in enterobacteria and independence of sigmaS in its acquisition.
Next Document: Characterization of species-specific genes using a flexible, web-based querying system.