Document Detail

Involvement of lupus enteritis in a patient with lupus cystitis and nephritis.
MedLine Citation:
PMID:  19776578     Owner:  NLM     Status:  MEDLINE    
We present the case of a patient with lupus enteritis accompanied by both lupus cystitis and lupus nephritis without a history of systemic lupus erythematosus. The patient had a 2-month history of diarrhea and pollakiuria and was admitted to our hospital. Physical examination showed abdominal tenderness. Laboratory data revealed reductions in both total protein and albumin, elevated serum creatinine levels, and elevated antinuclear and anti-Smith antibodies. Urinalysis revealed proteinuria. Stool and urine cultures were negative. Abdominal computed tomography revealed diffuse edematous wall thickening, dilatation of the small intestine suggesting paralytic ileus, and irregular wall thickening of the urinary bladder. Histological results of the cystic and renal biopsies revealed interstitial cystitis and membranous nephropathy which were suggestive of lupus cystitis and lupus nephritis, respectively. The patient's gastrointestinal symptoms were finally diagnosed as resulting from lupus enteritis. After initiating 30 mg oral prednisolone daily, the diarrhea and pollakiuria subsided, and renal function became normal. Lupus enteritis should always be considered in the differential diagnosis when patients complaining of chronic diarrhea of unknown etiology are encountered.
Reiko Akitake; Hiroshi Nakase; Satoru Ueno; Shinichi Miyamoto; Noriyuki Iehara; Tsutomu Chiba
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-16
Journal Detail:
Title:  Digestion     Volume:  80     ISSN:  1421-9867     ISO Abbreviation:  Digestion     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-15     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  160-4     Citation Subset:  IM    
Copyright Information:
Copyright 2009 S. Karger AG, Basel.
Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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MeSH Terms
Cystitis, Interstitial / complications*
Enteritis / complications*
Lupus Erythematosus, Systemic / complications*
Lupus Nephritis / complications*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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