| Involvement of the hypothalamo-pituitary-adrenal axis in the control of circadian blood pressure rhythm. | |
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MedLine Citation:
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PMID: 3241233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The circadian blood pressure rhythm was compared between patients with Cushing's syndrome and those with essential hypertension or primary aldosteronism. In patients with essential hypertension or primary aldosteronism, clear nocturnal falls in systolic and diastolic blood pressure and the heart rate were observed. In contrast, in patients with Cushing's syndrome there was no nocturnal fall in blood pressure, and even a rise in some cases. In all cases with Cushing's syndrome, there was a nocturnal fall in the heart rate. Exogenous glucocorticoid abolished a nocturnal fall of blood pressure in patients with chronic glomerulonephritis or systemic lupus erythematosus, but did not affect nocturnal falls in the heart rate. These results indicate that the normal circadian rhythm of blood pressure may be regulated, at least in part, by the hypothalamopituitary-adrenal system. |
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Authors:
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M Munakata; Y Imai; K Abe; S Sasaki; N Minami; H Sekino; K Yoshinaga |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of hypertension. Supplement : official journal of the International Society of Hypertension Volume: 6 ISSN: 0952-1178 ISO Abbreviation: J Hypertens Suppl Publication Date: 1988 Dec |
Date Detail:
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Created Date: 1989-05-18 Completed Date: 1989-05-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8501422 Medline TA: J Hypertens Suppl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: S44-6 Citation Subset: IM |
Affiliation:
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Department of Medicine, Tohoku University School of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Pressure* Circadian Rhythm* Cushing Syndrome / physiopathology Glomerulonephritis / physiopathology Heart Rate Humans Hyperaldosteronism / physiopathology Hypertension / physiopathology* Hypothalamo-Hypophyseal System / physiology* Lupus Erythematosus, Systemic / physiopathology Pituitary-Adrenal System / physiology* |
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