| Involvement of eosinophils in acute myeloid leukaemia with monosomy 7 demonstrated by fluorescence in situ hybridization. | |
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MedLine Citation:
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PMID: 7803286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Monosomy 7 is the commonest monosomy in acute myeloid leukaemia (AML). A patient with AML and monosomy 7 was investigated by fluorescence in situ hybridization. Monosomy 7 could be demonstrated in the blasts and also in mature eosinophils, but apparently not in lymphocytes. Monosomy 7 may occur in a multipotential myeloid progenitor cell as part of the multi-step leukaemogenic process. |
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Authors:
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Y L Kwong; L C Chan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: British journal of haematology Volume: 88 ISSN: 0007-1048 ISO Abbreviation: Br. J. Haematol. Publication Date: 1994 Oct |
Date Detail:
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Created Date: 1995-02-02 Completed Date: 1995-02-02 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372544 Medline TA: Br J Haematol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 389-91 Citation Subset: IM |
Affiliation:
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University Department of Medicine, Queen Mary Hospital, Hong Kong. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Bone Marrow / pathology Chromosomes, Human, Pair 7* Eosinophils / pathology* Female Humans In Situ Hybridization, Fluorescence Leukemia, Myeloid, Acute / genetics*, pathology Monosomy* |
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