| Involvement of adenovirus in clinical mononucleosis-like syndromes in young children. | |
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MedLine Citation:
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PMID: 15891915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although Epstein-Barr virus (EBV) commonly causes infectious mononucleosis (IM) or IM-like syndromes, other agents can be implicated. In this study, viral and parasitic screening was performed to determine the etiological agent of pediatric IM-like syndromes in 38 children. Adenovirus was the agent most frequently detected (47.3%), followed by EBV (31.5%) and cytomegalovirus (2.6%). Although the statistically significant difference between viral detection rates observed in patients who fulfilled clinical and hematological criteria and detection rates in those who presented clinical symptoms only (91.6% vs. 64.3%) indicates that hematological abnormalities are common in viral IM-like syndromes, the existence of syndromes of viral etiology without hematological criteria cannot be discarded. A further analysis showed an absence of lymphocytosis in adenovirus infections as well as a low number (14.3%) of EBV infections associated with increased neutrophils. These data suggest the usefulness of appropriate virological techniques for the detection of adenovirus in pediatric IM-like syndromes. |
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Authors:
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S Melón; S Méndez; B Iglesias; J A Boga; M Rodríguez; J L Fanjul; F J Méndez; M de Oña |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: 24 ISSN: 0934-9723 ISO Abbreviation: Eur. J. Clin. Microbiol. Infect. Dis. Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-06-02 Completed Date: 2005-08-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: Germany |
Other Details:
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Languages: eng Pagination: 314-8 Citation Subset: IM |
Affiliation:
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Servicio de Microbiología I, Hospital Universitario Central de Asturias, Celestino Villamil s/n, 33006 Oviedo, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenovirus Infections, Human
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physiopathology*,
virology* Child Child, Preschool Female Humans Infant Infectious Mononucleosis / virology* Male |
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