| Involution of multicystic dysplastic kidney: Is it predictable? | |
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MedLine Citation:
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PMID: 22687342 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the clinical course of multicystic dysplastic kidney (MCDK) and to reveal any criteria indicating spontaneous involution. MATERIAL METHODS: Hospital records of patients with MCDK followed in two different institutions in 1994-2009 were reviewed and data were analyzed regarding involution. RESULTS: Records of 96 patients were reviewed, of whom 46 were diagnosed antenatally and followed for more than 1 year. Fourteen patients had undergone nephrectomy. There was one case of hypertension which resided with nephrectomy. There was no malignancy. Involution rate was 53.6% (15/28) for right-sided and only 16.7% (3/18) for left-sided kidneys. The initial size of the kidney was found to be another predictive parameter for involution. Initial sizes of 43 (15 involuted and 28 non-involuted) kidneys were documented. Mean standard deviation score for involuting and non-involuting kidneys was -3.19 and 3.12, respectively. The chance of involution for a large kidney on the left was zero; however, involution risk for a small right-sided kidney was 67%. CONCLUSION: Reviewing a 15-year period of our patient records conveyed data supporting current literature mainly encouraging non-operative management of MCDK. Further studies are required; however, our two objective indicators, the initial size and side of dysplastic kidney, may contribute to the management. |
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Authors:
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Sibel Tiryaki; Akgun Yilmaz Alkac; Erkin Serdaroglu; Mustafa Bak; Ali Avanoglu; Ibrahim Ulman |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-9 |
Journal Detail:
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Title: Journal of pediatric urology Volume: - ISSN: 1873-4898 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101233150 Medline TA: J Pediatr Urol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Ege University, Faculty of Medicine, Department of Pediatric Surgery, Division of Pediatric Urology, Izmir, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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