Document Detail

Investigator bias in urodynamic studies for functional urinary incontinence.
MedLine Citation:
PMID:  19695596     Owner:  NLM     Status:  MEDLINE    
PURPOSE: In the setting of the European Bladder Dysfunction Study, a multicenter, randomized, controlled trial of treatment options for functional incontinence in children, we assessed the concordance between reported and reviewed urodynamic scores. MATERIALS AND METHODS: A total of 97 children with clinically diagnosed urge syndrome and 105 with clinically diagnosed dysfunctional voiding enrolled in the European Bladder Dysfunction Study and underwent full urodynamic studies before and immediately after treatment for urinary incontinence. Photocopies of 72% of the original urodynamic recordings were available for blinded review. RESULTS: The concordance for detrusor overactivity throughout the filling phase was 37% in urge syndrome cases and for increased pelvic floor activity during voiding it was 81% in dysfunctional voiding cases. Differences in original and reviewed scores were equally distributed among participating centers. CONCLUSIONS: Concordance between original and reviewed urodynamic scores was low for detrusor overactivity. Concordance was acceptable for increased pelvic floor activity during voiding but was not specific for dysfunctional voiding. Since interpreting urodynamic studies is based on pattern recognition, investigator bias can only be compensated for by blinded review of the actual recordings.
An Bael; John Verhulst; Hildegard Lax; Herbert Hirche; Jan D van Gool;
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Publication Detail:
Type:  Journal Article     Date:  2009-08-20
Journal Detail:
Title:  The Journal of urology     Volume:  182     ISSN:  1527-3792     ISO Abbreviation:  J. Urol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-14     Completed Date:  2009-10-29     Revised Date:  2009-12-16    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1949-52     Citation Subset:  AIM; IM    
Department of Pediatrics, University Hospital, Antwerp, Belgium.
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MeSH Terms
Observer Variation
Randomized Controlled Trials as Topic
Urinary Incontinence / physiopathology*
Comment In:
J Urol. 2009 Oct;182(4 Suppl):1953; discussion 1953   [PMID:  19695597 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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