Document Detail


Investigation of the veins in patients with Behçet's disease with no known vascular event by Doppler ultrasonography.
MedLine Citation:
PMID:  20981428     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In Behçet's disease, deep venous thrombosis occurs primarily in the lower extremities. Total recanalization rate is low, so thrombotic segment could be detected by imaging afterward. For disclosing vein involvement, leg swelling is commonly queried in the history taking in those patients. However, there are no data about the presence of "silent" thrombosis in patients with BD. We aimed at investigating the integrity of venous vessels in BD, without any known vascular event by using Doppler ultrasonography (DU). Patients having past events revealed in the vascular questionnaire or physical findings attributable to vascular disease were excluded. Various degree of venous insufficiency was detected in 74 patients in BD (74%), 24 out of 33 patients (72%) in AS and in 8 out of 34 (25%) in HC group. All were at the lower extremities, and there is no difference in the frequency between BD and AS, while both were significantly higher than in HC (P = 0.001, and 0.004, respectively). Six patients with BD (6%) have chronic venous thrombi at the lower extremities and none in either AS and HC. As a non-invasive method, DU of lower extremities may disclose "silent" thrombosis. Venous insufficiency in those patients should be considered cautiously as an indicator of vein involvement.
Authors:
Bunyamin Kisacik; Cem Oren; Timucin Kasifoglu; Sedat Yilmaz; Omer Yilmaz; Ismail Simsek; Hakan Erdem; Salih Pay; Mutlu Saglam; Ayhan Dinc
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Publication Detail:
Type:  Journal Article     Date:  2010-10-28
Journal Detail:
Title:  Rheumatology international     Volume:  32     ISSN:  1437-160X     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  303-6     Citation Subset:  IM    
Affiliation:
Division of Rheumatology, Department of Internal Medicine, Gulhane School of Medicine, Ankara, Turkey.
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