Document Detail


Investigation of varicella-zoster virus infection of lymphocytes by in situ hybridization.
MedLine Citation:
PMID:  2539528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Peripheral blood mononuclear cells harboring viral gene sequences were detected during primary varicella-zoster virus (VZV) infection of the human host and the strain 2 guinea pig by in situ hybridization with a 3H-labeled VZV DNA probe. Activated T lymphocytes were permissive for VZV infection at low frequency in vitro.
Authors:
C M Koropchak; S M Solem; P S Diaz; A M Arvin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of virology     Volume:  63     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-05-18     Completed Date:  1989-05-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2392-5     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Stanford University School of Medicine, California 94305.
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MeSH Terms
Descriptor/Qualifier:
Animals
DNA Probes
DNA, Viral / analysis
Guinea Pigs
Herpes Zoster / diagnosis*
Herpesvirus 3, Human / genetics*
Humans
Lymphocyte Activation
Lymphocytes / microbiology*
Nucleic Acid Hybridization
Species Specificity
Grant Support
ID/Acronym/Agency:
AI 00624/AI/NIAID NIH HHS; AI 20459/AI/NIAID NIH HHS; AI 22280/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/DNA Probes; 0/DNA, Viral
Comments/Corrections

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