| Investigation of potential antibacterial properties of methanol extracts from fungus Ganoderma applanatum. | |
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MedLine Citation:
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PMID: 16899973 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study we searched for antibacterial compounds in methanol extracts of three layers (tube layer, context and cutis) of Ganoderma applanatum fruit body against Bacillus subtilis ATCC 6051 as a gram-positive bacterium and Escherichia coli ATCC 25922 and Pseudomonas syringae pv. syringae DPIC 219 as gram-negative bacteria. We found antibacterial properties in all three layers only against gram-negative bacteria. The fractions were isolated and purified by thin layer chromatography (TLC) and high-performance liquid chromatography. After purification, four major compounds - A, B, C and D - were tested for antibacterial properties, and B and D were found to possess antibacterial properties. The results of TLC and spectral data, including mass spectra and (1)H NMR of compounds B and C, showed that they were saturated fatty acids and compound D was palmitic acid (hexadecanoic acid) (16:0). |
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Authors:
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Mohammad-Fata Moradali; Hossien Mostafavi; Ghorban-Ali Hejaroude; Abbas Sharifi Tehrani; Mehrdad Abbasi; Shirin Ghods |
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Publication Detail:
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Type: Journal Article Date: 2006-08-04 |
Journal Detail:
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Title: Chemotherapy Volume: 52 ISSN: 0009-3157 ISO Abbreviation: Chemotherapy Publication Date: 2006 |
Date Detail:
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Created Date: 2006-08-23 Completed Date: 2006-12-07 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0144731 Medline TA: Chemotherapy Country: Switzerland |
Other Details:
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Languages: eng Pagination: 241-4 Citation Subset: IM |
Affiliation:
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Plant Protection Department, Faculty of Agriculture, Tehran University, Karaj, Iran. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacology* Ganoderma / chemistry* Gram-Negative Bacteria / drug effects* Gram-Positive Bacteria / drug effects* Methanol / chemistry Microbial Sensitivity Tests Phytotherapy* Plant Extracts / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Plant Extracts; 67-56-1/Methanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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