Document Detail

Investigation of the most effective provocation test for patients with coronary spastic angina: usefulness of accelerated exercise following hyperventilation.
MedLine Citation:
PMID:  10084369     Owner:  NLM     Status:  MEDLINE    
This study sought to compare the clinical usefulness of the hyperventilation plus cold stress test or the hyperventilation combined with accelerated exercise test with other single tests in patients with coronary spastic angina. The study examined 24 patients (23 men, mean age 66 years) with angiographically confirmed coronary spastic angina and less than 50% stenosis. Moreover, none had spontaneous ST segment elevation before the study. Under no medication for at least 24 h prior, 4 procedures were performed from 09.00 h to 11.00 h: (i) a hyperventilation test for 5 min (HV(5)); (ii) HV(5) combined with a cold stress test for the last 2 min (HV(5)+CS(2)); (iii) a treadmill exercise test based on Bruce's protocol (TM(3)); and (iv) a treadmill exercise test accelerated at 1 min intervals according to Bruce's protocol immediately after HV(5) (HV(5)+TM(1)). The rate of appearance of chest pain and ischemia-induced ECG changes due to HV(5)+TM(1) were significantly higher than the other 3 tests. HV(5)+CS(2) was not superior to HV(5) alone. The incidence of provoked ST segment elevation due to HV(5)+TM(1) was higher than with the other 3 procedures. Thus, in patients with coronary spastic angina, no spontaneous ST segment elevation and near normal coronary arteries, HV(5)+CS(2) was no more useful than HV(5) alone. It is recommended that the newly designed HV(5)+TM(1) combination test be used for documenting evidence of ischemia in patients with coronary spastic angina, low disease activity and near normal coronary arteries.
S Sueda; H Saeki; T Otani; N Ochi; H Kukita; H Kawada; S Matsuda; T Uraoka
Related Documents :
7608439 - Estimates of myocardium at risk and collateral flow in acute myocardial infarction usin...
10376179 - Qrs prolongation on the signal-averaged electrocardiogram versus st-segment changes on ...
18340219 - Missed diagnosis of the diagnosis codes: comparison of international classification of ...
18923239 - Clinical and prognostic comparison between left ventricular transient dyskinesia and a ...
2667729 - Actions of nisoldipine in cardiovascular disease.
7618619 - Failure of protective effect of captopril and enalapril on exercise and dipyridamole-in...
10972599 - Milrinone, not epinephrine, improves left ventricular compliance after cardiopulmonary ...
10652189 - Heat production of atherosclerotic plaques and inflammation assessed by the acute phase...
18651519 - Cardiac rupture risk estimation in patients with acute myocardial infarction treated wi...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  63     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-05-24     Completed Date:  1999-05-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  85-90     Citation Subset:  IM    
Department of Cardiology, Saiseikai Saijo Hospital, Ehime Prefecture, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acetylcholine / diagnostic use
Angina Pectoris, Variant / diagnosis*,  etiology,  physiopathology
Cold Temperature / diagnostic use*
Coronary Angiography
Coronary Disease / complications
Exercise Test*
Hyperventilation* / physiopathology
Middle Aged
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Relationship between brain atrophy estimated by a longitudinal computed tomography study and blood p...
Next Document:  Percutaneous transluminal coronary angioplasty, alone or in combination with urokinase therapy, duri...