Document Detail

Investigation of the functional three-dimensional anatomy of the human cystic duct: a single helix?
MedLine Citation:
PMID:  16287091     Owner:  NLM     Status:  MEDLINE    
Clinical research into the formation of gallstones has indicated that the anatomy of the cystic duct is one of a number of factors contributing to the formation of gallstones. The cystic duct allows low-viscosity hepatic bile to enter the gallbladder under low pressure and the expulsion of a more viscous gallbladder bile, but little is known about this transport mechanism and the effect of anatomical variations in structure. This article describes the variation in geometry of the cystic duct, obtained from acrylic resin casts of the neck and first part of the cystic duct in gallbladders removed for gallstone disease and obtained from patients undergoing partial hepatectomy for metastatic disease. The data obtained allowed us to formulate a number of standard terms for describing cystic duct morphology and demonstrate that the term "spiral valve" is only partially correct when describing the duct anatomy. In over half of the casts, spiraling was not the dominant feature of the cystic duct. Additionally, the term valve implies active resistance to flow in one direction, whereas the internal baffles of the cystic duct would serve to regulate bile flow in both directions. These data are useful for realistic 3D modeling of fluid-structure interactions of the flow of bile in the human cystic duct.
N C Bird; R C Ooi; X Y Luo; S B Chin; A G Johnson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical anatomy (New York, N.Y.)     Volume:  19     ISSN:  0897-3806     ISO Abbreviation:  Clin Anat     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-30     Completed Date:  2006-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809128     Medline TA:  Clin Anat     Country:  United States    
Other Details:
Languages:  eng     Pagination:  528-34     Citation Subset:  IM    
Liver Research Group, University of Sheffield, Sheffield, United Kingdom.
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MeSH Terms
Bile Ducts / pathology
Cystic Duct / pathology*,  surgery
Gallbladder / pathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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