| Investigation of facial recognition memory and happy and sad facial expression perception: an fMRI study. | |
| | |
MedLine Citation:
|
PMID: 9849722 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We investigated facial recognition memory (for previously unfamiliar faces) and facial expression perception with functional magnetic resonance imaging (fMRI). Eight healthy, right-handed volunteers participated. For the facial recognition task, subjects made a decision as to the familiarity of each of 50 faces (25 previously viewed; 25 novel). We detected signal increase in the right middle temporal gyrus and left prefrontal cortex during presentation of familiar faces, and in several brain regions, including bilateral posterior cingulate gyri, bilateral insulae and right middle occipital cortex during presentation of unfamiliar faces. Standard facial expressions of emotion were used as stimuli in two further tasks of facial expression perception. In the first task, subjects were presented with alternating happy and neutral faces; in the second task, subjects were presented with alternating sad and neutral faces. During presentation of happy facial expressions, we detected a signal increase predominantly in the left anterior cingulate gyrus, bilateral posterior cingulate gyri, medial frontal cortex and right supramarginal gyrus, brain regions previously implicated in visuospatial and emotion processing tasks. No brain regions showed increased signal intensity during presentation of sad facial expressions. These results provide evidence for a distinction between the neural correlates of facial recognition memory and perception of facial expression but, whilst highlighting the role of limbic structures in perception of happy facial expressions, do not allow the mapping of a distinct neural substrate for perception of sad facial expressions. |
| | |
Authors:
|
M L Phillips; E T Bullmore; R Howard; P W Woodruff; I C Wright; S C Williams; A Simmons; C Andrew; M Brammer; A S David |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Psychiatry research Volume: 83 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 1998 Sep |
Date Detail:
|
Created Date: 1999-02-26 Completed Date: 1999-02-26 Revised Date: 2010-08-25 |
Medline Journal Info:
|
Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: IRELAND |
Other Details:
|
Languages: eng Pagination: 127-38 Citation Subset: IM |
Affiliation:
|
Department of Psychological Medicine, Institute of Psychiatry, London, UK. spmamlp@iop.bpmf.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Attention / physiology Brain / physiology Brain Mapping Dominance, Cerebral / physiology Emotions / physiology* Facial Expression* Female Humans Limbic System / physiology Magnetic Resonance Imaging* Male Mental Recall / physiology* Pattern Recognition, Visual / physiology* Social Perception* |
| Grant Support | |
ID/Acronym/Agency:
|
//Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: ACOG practice bulletin. Premature rupture of membranes. Clinical management guidelines for obstetric...
Next Document: Cerebral CT findings in male opioid-dependent patients: stereological, planimetric and linear measur...