| Investigation of bound water in frozen precancerous rat liver tissue by proton NMR. | |
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MedLine Citation:
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PMID: 7763001 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The proton NMR spin lattice relaxation times of bound water (T1b) were studied on frozen rat liver samples during the precancerous step of cancer induction by diethylnitrosamine. Two components of the T1b were found, which show a different temperature dependence of their relative magnetization. Four different steps were identified during the experimental cancer induction according to 1H NMR findings, while only three were distinguished after histological examination. The results point to the influence of cross-relaxation and corroborate previous reports on differences observed between the heat capacity of normal and tumorous tissues. |
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Authors:
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D Pouliquen; M C Rousselet; J P Saint André; P Jallet; J J Le Jeune |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Anticancer research Volume: 15 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 1995 Mar-Apr |
Date Detail:
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Created Date: 1995-06-23 Completed Date: 1995-06-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: GREECE |
Other Details:
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Languages: eng Pagination: 321-9 Citation Subset: IM |
Affiliation:
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Laboratoire de Biophysique, Faculté de Médecine, Angers, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Water* Diethylnitrosamine Freezing Liver / chemistry*, drug effects, pathology Liver Neoplasms, Experimental / chemically induced* Magnetic Resonance Spectroscopy Male Precancerous Conditions / chemically induced, metabolism*, pathology Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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55-18-5/Diethylnitrosamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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