Document Detail


Investigation of blood flow in meningothelial and fibrous meningiomas by xenon-enhanced CT scanning.
MedLine Citation:
PMID:  11045026     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated whether xenon-enhanced computed tomography was able to separate meningothelial meningioma from fibrous meningioma. Cerebral blood flow was studied by xenon-enhanced computed tomography in six patients with incidentally detected intracranial meningiomas. All of the tumors were small (< 32 mm) and there was little or no peritumoral edema. Three patients had meningothelial meningioma and three patients had fibrous meningioma. The tumor blood flow and the contralateral tissue blood flow were determined. The ratio of these parameters was 1.753 +/- 0.467 for meningothelial meningiomas and 0.809 +/- 0.105 for fibrous meningiomas, with a significant difference between the two tumor subtypes (p = 0.0185). There was no correlation between the signal intensity on magnetic resonance imaging and tumor subtype, and the findings on cerebral angiography also did not indicate the subtype. In conclusion, xenon-enhanced computed tomography showed a difference between smaller meningothelial and fibrous meningiomas in patients with normal surrounding brain tissue. We could not confirm that xenon-enhanced computed tomography was able to distinguish the subtype of meningioma because of the small number of subjects in this study, but our findings might expand interest in the clinical use of this method.
Authors:
M Nakatsuka; S Mizuno
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurological research     Volume:  22     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-02-06     Completed Date:  2001-02-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  615-9     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Chita Kousei Hospital, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Cerebral Angiography
Female
Gadolinium
Humans
Magnetic Resonance Imaging
Meningeal Neoplasms / blood supply*,  classification,  pathology,  radiography*
Meningioma / blood supply*,  classification,  pathology,  radiography*
Middle Aged
Regional Blood Flow
Tomography, X-Ray Computed / methods
Xenon
Chemical
Reg. No./Substance:
7440-54-2/Gadolinium; 7440-63-3/Xenon

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