Document Detail


Investigation of biochemical and haematological side-effects of enrofloxacin in dogs.
MedLine Citation:
PMID:  11515313     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present study, effects of enrofloxacin on biochemical, haematological and blood gas parameters were investigated. Changes in laboratory parameters were monitored during the treatment period. Enrofloxacin was administered (5 mg/kg intramuscularly, once daily) to 10 healthy dogs for 14 days. Acidosis and temporary increases in aspartate aminotransferase, indirect bilirubin, sodium, partial pressure of CO2 and mean corpuscular volume levels as well as decreased levels of inorganic phosphorus, ionized calcium, potassium, partial pressure of O2 and standard bicarbonate were observed. The results of this study suggest that these observed effects of enrofloxacin on blood gas parameters should be taken into consideration in long-term use of the drug.
Authors:
B Traş; M Maden; A L Baş; M Elmas; E Yazar; T Civelek
Related Documents :
466413 - Brain sodium uptake after choroid plexectomy.
12790663 - Direct current electrical field effects on intact plant organs.
8912743 - Efficacy of cardiopulmonary resuscitation using intratracheal insufflation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine     Volume:  48     ISSN:  0931-184X     ISO Abbreviation:  J Vet Med A Physiol Pathol Clin Med     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-08-22     Completed Date:  2001-10-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100955112     Medline TA:  J Vet Med A Physiol Pathol Clin Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
Affiliation:
Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acidosis / chemically induced,  veterinary
Animals
Anti-Infective Agents / adverse effects*
Aspartate Aminotransferases / metabolism
Bilirubin / analysis
Blood Gas Analysis / veterinary*
Dog Diseases / chemically induced*
Dogs
Female
Fluoroquinolones*
Quinolones / adverse effects*
Sodium / analysis
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Fluoroquinolones; 0/Quinolones; 635-65-4/Bilirubin; 7440-23-5/Sodium; 93106-60-6/enrofloxacin; EC 2.6.1.1/Aspartate Aminotransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Immunohistological demonstration of erythroid cells in canine bone marrow.
Next Document:  Aggressive behavior in combat veterans with post-traumatic stress disorder.