| Investigation of bilirubin removal by NK-110 resin hemoperfusion in jaundiced dogs. | |
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MedLine Citation:
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PMID: 3781664 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A jaundiced dog model was made by common bile duct-inferior vena cava shunt with a silicon rubber tube. Blood bilirubin levels increased from 0.25 +/- 0.16 (SD) mg% to 15 +/- 1.4 (SD) mg%. These dog models were treated with a column containing 200 gm of macroreticular resin NK-110 which was linked between the femoral artery and vein. The rate of blood flow through the column was 200 ml/min. It was shown that total bilirubin reduced from 15 +/- 1.4 (SD) to 7.4 +/- 0.61 (SD), conjugated bilirubin decreased from 6.97 +/- 0.63 to 3.5 +/- 0.33 (SD) and unconjugated bilirubin from 7.8 +/- 2.1 to 4.2 +/- 0.4 (SD). There were no significant changes in protein, electrolyte, blood gases and acid base balance. Results show that NK-110 resin has good blood-compatible and adsorption properties. |
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Authors:
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S Ji-Chang; Q Shao-Cheng; Z Chen-Yang; N Fu-Hua; H Shao-Ming; L Tao; C Run-Hai; C Chang-Zhi; T Ming-Rong; W Hui-Ming |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The International journal of artificial organs Volume: 9 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1986 Sep |
Date Detail:
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Created Date: 1987-01-16 Completed Date: 1987-01-16 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
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Languages: eng Pagination: 327-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adsorption Animals Bilirubin / metabolism* Disease Models, Animal Dogs Female Hemoperfusion* Ion Exchange Resins Jaundice / therapy* Male Polystyrenes* Resins, Synthetic* |
| Chemical | |
Reg. No./Substance:
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0/Ion Exchange Resins; 0/Polystyrenes; 0/Resins, Synthetic; 106717-05-9/NK 110 resin; 635-65-4/Bilirubin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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