Document Detail

Investigation of auditory brainstem function in elderly diabetic patients with presbycusis.
MedLine Citation:
PMID:  19842349     Owner:  NLM     Status:  MEDLINE    
We performed brainstem auditory evoked potential (BAEP) examinations in 100 patients older than 60 years and having type I diabetes mellitus and presbycusis. The aim of our investigation was to compare the BAEP results of this group with those of healthy controls with presbycusis and to look for possible correlations between alteration of the auditory brainstem function and the aging of elderly diabetic patients. Absolute and interpeak latencies of all waves were prolonged significantly in the study group of diabetic patients. The amplitudes of all waves I through V were diminished in the study group as compared to those in the control group, with statistical significance present for all waves. Analysis of the latencies (waves I, II, I, and V), interpeak latencies (I-V), and amplitudes (I, II, III, and V) of BAEP revealed a significant difference between those of diabetics and those of healthy elderly controls with presbycusis. These data support a hypothesis that there is a brainstem neuropathy in diabetes mellitus that can be assessed with auditory brainstem response testing even in the group of elderly patients with sensorineural hearing loss.
Jelena Kovacií; Zoran Lajtman; Ivan Ozegović; Predrag Knezević; Tomislav Carić; Ana Vlasić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The international tinnitus journal     Volume:  15     ISSN:  0946-5448     ISO Abbreviation:  Int Tinnitus J     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-21     Completed Date:  2009-12-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612993     Medline TA:  Int Tinnitus J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  79-82     Citation Subset:  IM    
Department of Otorhinolaryngology, Odjel Klinicka Bolnica Dubrava, Zagreb, Croatia.
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MeSH Terms
Aged, 80 and over
Auditory Pathways / physiopathology
Brain Stem / physiopathology
Diabetes Mellitus, Type 1 / physiopathology*
Diabetic Neuropathies / physiopathology*
Evoked Potentials, Auditory, Brain Stem / physiology*
Middle Aged
Presbycusis / physiopathology*
Reaction Time / physiology
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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